[The predictive value of cyclic nucleotide ratio in the prognosis of experimental tumors].
Autor: | Rabinovich EI, Sokolova SN |
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Jazyk: | ruština |
Zdroj: | Voprosy onkologii [Vopr Onkol] 1996; Vol. 42 (4), pp. 45-8. |
Abstrakt: | The report deals with the predictive value of a procedure for lifetime detection of tumor in experimental animals. The database included the results of regular cAMP/cHMP tests carried out in 54 rats with radionuclide-inducted tumors and 24 tumor-free rats. The data were processes by statistical methods and the informative value was determined on the basis of standard recommendations. The test was shown to have high sensitivity (85.2%), sufficient predictive value (73%) and diagnostic effectiveness (68%). Application of the test in groups of humans at high risk of tumor development is discussed. |
Databáze: | MEDLINE |
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