Systemic lupus erythematosus in South African blacks: prospective study.

Autor: Jacyk WK; Department of Dermatology, University of Pretoria, Republic of South Africa., Steenkamp KJ
Jazyk: angličtina
Zdroj: International journal of dermatology [Int J Dermatol] 1996 Oct; Vol. 35 (10), pp. 707-10.
DOI: 10.1111/j.1365-4362.1996.tb00642.x
Abstrakt: Background: The aim of the study was to evaluate clinical and laboratory findings in black South African patients with systemic lupus erythematosus (SLE) and to compare these with findings in a group of white patients.
Materials and Methods: Forty black patients were studied. The group of exclusively white patients reported by Beutner et al. was used for comparison.
Results: A decreased frequency of malar rash, photosensitivity, and hematologic involvement was found in black patients. They had anti-Sm and anti-nRNP antibodies and low complement more often than white patients with SLE in Beutner et al. group.
Conclusions: More differences have been noted in laboratory than in clinical parameters and findings reported in African-Americans with SLE have been confirmed in black Africans. Ethnic factors may play a role in the symptomatology of SLE.
Databáze: MEDLINE
Externí odkaz: