| Autor: |
Murphy BA; Department of Pathology, North Carolina Baptist Hospitals, Incorporated, Bowman Gray School of Medicine, Winston-Salem 27157-1072, USA., Kilpatrick SE, Panella MJ, White WL |
| Jazyk: |
angličtina |
| Zdroj: |
Journal of cutaneous pathology [J Cutan Pathol] 1996 Aug; Vol. 23 (4), pp. 369-72. |
| DOI: |
10.1111/j.1600-0560.1996.tb01312.x |
| Abstrakt: |
Calcifying aponeurotic fibroma (CAF) is an unusual but well-characterized soft tissue neoplasm that typically involves the digits of children and frequently recurs locally. This report describes a case from the subcutis of the lumbosacral region. A 26-year-old man initially presented at age 3 and developed three recurrences over a 23-year period each at approximately 8-year intervals (ages 10, 18, and 26). The microscopic findings in all recurrences showed a lobulated, poorly circumscribed proliferation of dense fibrous tissue containing epithelioid-like fibroblasts, multinucleated cells, and islands of metaplastic chondroid differentiation with focal calcification. Despite origin from an unusual anatomic site, this case reported herein demonstrates the classical morphologic features and clinical history of CAF which showed little in the way of morphologic evolution despite 23 years of persistence. The clinical and histologic features helpful in distinguishing CAF from infantile fibromatosis and soft tissue chondroma are discussed. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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