| Autor: |
Wickramasinghe SN; Department of Haematology, Imperial College School of Medicine at St Mary's, London., Andrews VE, O'Hea AM |
| Jazyk: |
angličtina |
| Zdroj: |
British journal of haematology [Br J Haematol] 1996 Oct; Vol. 95 (1), pp. 73-6. |
| DOI: |
10.1046/j.1365-2141.1996.d01-1885.x |
| Abstrakt: |
Four patients with congenital dyserythropoiesis characterized by marked macrocytosis, little or no anaemia, and vitamin B12- and folate-independent megaloblastic erythropoiesis are reported. Their erythroblasts also showed various dysplastic changes but not those diagnostic for congenital dyserythropoietic anaemia (CDA) types I or III. The haematological features of the four patients, who included two siblings, resemble those of a previously reported patient and together these patients form a recognizable subgroup within those cases of CDA not belonging to CDA types I-III. In two of the cases studied, and possibly a third, the inheritance was as an autosomal recessive character. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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