| Autor: |
Makevnina LG; Institute of Biomedical Chemistry, Moscow, Russia., Nikonov AP, Goncharova VN, Morozova MS, Paskhina TS |
| Jazyk: |
angličtina |
| Zdroj: |
Immunopharmacology [Immunopharmacology] 1996 Jun; Vol. 33 (1-3), pp. 133-6. |
| DOI: |
10.1016/0162-3109(96)00023-9 |
| Abstrakt: |
Blood plasma kininogen (K), kininases (KS), kallikrein (KK), prekallikrein (PKK), and PGF2a were estimated in the common circulation of pregnant women during late saline-induced abortion and also in retroplacental blood after foetus delivery. The results provide evidence for intra-uterine kinin release from circulating blood K by locally activated KK from the very beginning of abortion. The greatest kinin release coincided with the strongest KS activity decrease at the time of foetus delivery. The pre-abortive KS levels correlated directly with abortus duration. Uterine PG biosynthesis was activated, but appeared to be a secondary process. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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