[Experimental data on bases of MAC of piroxicam in the air of workplace].

Autor: Bogachuk GP, Barkova NP, Andropova SN, Gushchina AA, Portianoĭ AA
Jazyk: ruština
Zdroj: Meditsina truda i promyshlennaia ekologiia [Med Tr Prom Ekol] 1996 (4), pp. 26-8.
Abstrakt: The experiments on white rats, mice, guinea pigs, rabbits studied inhalation toxicity of piroxicam. The substance having strong cumulation (Jcum = 0.5) and embryotoxic effects (Limap = 0.1 mg/cum) is assigned to a group of parenchymatous poisons. Toxicometry data (CL50 = 250 mg/cum, Limac = 50 mg/cum, Limch = 0.5 mg/cum) prove the first jeopardy grade of the substance. The recommended MAC for workplace is 0.05 mg/cum.
Databáze: MEDLINE