Cloning and sequence analysis of a hypothalamic cDNA encoding a D1c dopamine receptor in tilapia.

Autor: Lamers AE; Department of Animal Physiology, Faculty of Science, University of Nijmegen, The Netherlands., Gröneveld D, de Kleijn DP, Geeraedts FC, Leunissen JA, Flik G, Wendelaar Bonga SE, Martens GJ
Jazyk: angličtina
Zdroj: Biochimica et biophysica acta [Biochim Biophys Acta] 1996 Jul 31; Vol. 1308 (1), pp. 17-22.
DOI: 10.1016/0167-4781(96)00086-3
Abstrakt: Physiological and pharmacological studies have indicated that during acid stress a D1-like dopamine receptor becomes functional on intermediate pituitary melanocyte-stimulating hormone cells of tilapia (Oreochromis mossambicus). As a first step towards physiological expression studies we isolated a D1-like dopamine receptor from a tilapia hypothalamus cDNA library. Construction of a phylogenetic tree of most of the D1-like receptors known in human, rat, Xenopus, goldfish and Drosophila revealed that the here presented clone is most likely the tilapia equivalent of the Xenopus D1c dopamine receptor.
Databáze: MEDLINE