Developmental patterns of plasma TSH, T4 and T3 in rats deprived of light from birth.

Autor: Ooka-Souda S, Draves DJ, Timiras PS
Jazyk: angličtina
Zdroj: Mechanisms of ageing and development [Mech Ageing Dev] 1977 Jul-Aug; Vol. 6 (4), pp. 287-91.
DOI: 10.1016/0047-6374(77)90030-6
Abstrakt: Plasma levels of TSH, T4 and T3 in the rat show characteristic developmental patterns within the first postnatal month, with TSH reaching a peak on day 13, T4 on day 16 and T3 on day 20. In dark-reared rats, a significant reduction in plasma T3 associated with low plasma T4 as well as high plasma TSH suggest that light-deprivation from birth impairs and/or delays maturation of pituitary-thyroid axis.
Databáze: MEDLINE