| Autor: |
Traeger SM; Department of Internal Medicine, Critical Care Service, SUMMA Health System/Akron City Hospital, Akron, Ohio, USA., Bonfiglio MF, Wilson JA, Martin BR, Nackes NA |
| Jazyk: |
angličtina |
| Zdroj: |
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [Clin Infect Dis] 1995 Dec; Vol. 21 (6), pp. 1504-6. |
| DOI: |
10.1093/clinids/21.6.1504 |
| Abstrakt: |
We describe four patients who had seizures while receiving ofloxacin; no other causes were evident. Common factors among all patients included advanced age and use of a high-dose regimen. The renal insufficiency of three patients and the timing of the seizures implicate accumulation of ofloxacin as a contributing factor. Other potentially related factors included electrolyte abnormalities and prior neurological insult. Improved awareness of and further investigation into the neurotoxic effects of ofloxacin may enhance its safe use. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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