| Autor: |
Sanfilipo M; Department of Psychiatry, New York Veterans Affairs Medical Center, 10010, USA., Wolkin A, Angrist B, van Kammen DP, Duncan E, Wieland S, Cooper TB, Peselow ED, Rotrosen J |
| Jazyk: |
angličtina |
| Zdroj: |
Psychopharmacology [Psychopharmacology (Berl)] 1996 Jan; Vol. 123 (2), pp. 211-4. |
| DOI: |
10.1007/BF02246180 |
| Abstrakt: |
The purpose of this study was to assess further the effect of amphetamine on negative symptoms of schizophrenia. Thirty-seven schizophrenic males meeting DSM-III criteria were rated with the Brief Psychiatric Rating Scale, the Abrams and Taylor Scale, and the Abnormal Involuntary Movements Scale before and after double-blind administration of either amphetamine (n = 26) or placebo (n = 11). Our results indicated that amphetamine administration generally did not improve negative symptoms, even when accounting for changes in positive symptoms. However, greater baseline negative symptoms were associated with a modest diminution after amphetamine treatment. Therefore, amphetamine may modestly improve negative symptoms in those schizophrenics in whom this symptomatology is more severe. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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