| Autor: |
Zipprich DA; Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA., Owen CH, Lewis CW, Gall SA Jr, Davis JW, Kisslo JA, Glower DD |
| Jazyk: |
angličtina |
| Zdroj: |
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography [J Am Soc Echocardiogr] 1996 May-Jun; Vol. 9 (3), pp. 231-40. |
| DOI: |
10.1016/s0894-7317(96)90135-2 |
| Abstrakt: |
The Frank-Starling relationship between left ventricular stroke work and end-diastolic minor-axis cross-sectional area was evaluated as a load-insensitive measure of inotropic state by two-dimensional echocardiography in 10 conscious dogs. Stroke work was calculated as the product of systolic change in cross-sectional area and either (1) beat-to-beat mean arterial pressure or (2) initial systolic blood pressure. Both Frank-Starling relationships were highly linear during preload variation (mean r = 0.96), sensitive to the inotropic state (slope increase with calcium 51% +/- 43% and 62% +/- 53%, respectively), and insensitive to afterload (r < 0.4, slope or x intercept versus afterload). Thus the Frank-Starling relationships derived from two-dimensional echocardiographic images and peripheral arterial pressure may be a useful and practical means of assessing inotropic state with minimally invasive measurements. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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