| Autor: |
Berenguer J; Servicio de Microbiología Clínica y Enfermedades Infecciosas, Hospital General Universitario Gregorio Marañón, Madrid, Spain., Diaz-Guerra TM, Ruiz-Diez B, Bernaldo de Quiros JC, Rodriguez-Tudela JL, Martinez-Suarez JV |
| Jazyk: |
angličtina |
| Zdroj: |
Journal of clinical microbiology [J Clin Microbiol] 1996 Jun; Vol. 34 (6), pp. 1542-5. |
| DOI: |
10.1128/jcm.34.6.1542-1545.1996 |
| Abstrakt: |
We describe a patient with AIDS who simultaneously developed Candida meningitis with three positive cerebrospinal fluid cultures and oral candidiasis. This patient also had a history or recurrent episodes of oral candidiasis treated with fluconazole. The patient did not respond to this therapy but was cured with amphotericin B and flucytosine. In vitro susceptibility tests revealed that each infection was caused by fluconazole-resistant Candida albicans isolates. Strain delineation by karyotyping, NotI restriction pattern analysis, hybridization with the specific probe 27A, and PCR fingerprinting with the phage M13 core sequence clearly demonstrated that meningitis and oral thrush were caused by two genetically different isolates. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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