[Familial erythermalgia treated with pizotifen].
| Autor: | Guillet MH; Service de Dermatologie, CHU Brest., Le Noach E, Milochau P, Sassolas B, Guillet G |
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| Jazyk: | francouzština |
| Zdroj: | Annales de dermatologie et de venereologie [Ann Dermatol Venereol] 1995; Vol. 122 (11-12), pp. 777-9. |
| Abstrakt: | Introduction: Primary erythermalgia is a rare acrosyndrome due to paroxystic arteriolar dilatation of extremities that become red and congested with warmth and burning sensation or pain. Observation: We report herein the observation of a primary erythermalgia affecting 3 degrees in the same family (grandfather, uncle/mother, and children with early onset at 6 years): pizotifene, an antiserotoninergic drug proved to be effective in mother and 14-year-old child who had never drawn benefit from any previous treatment. Discussion: Several etiologies may be responsible for erythermalgia according to the clinical type: primary erythermalgia with pediatric onset, and secondary erythermalgia as a reaction to myeloproliferation, other diseases, drug or heavy metal poisoning. Pathophysiology of primary erythermalgia is not clearly understood and the main concern is therapy: in this respect, pizotifene deserves to be considered as a valuable possibility. |
| Databáze: | MEDLINE |
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