| Autor: |
Allen JW, Shuler CF, Mendes RW, Latt SA |
| Jazyk: |
angličtina |
| Zdroj: |
Cytogenetics and cell genetics [Cytogenet Cell Genet] 1977; Vol. 18 (4), pp. 231-7. |
| DOI: |
10.1159/000130765 |
| Abstrakt: |
A small tablet of 5-bromodeoxyuridine (BrdU), implanted subcutaneously in a mouse, provides sustained release of base analog sufficient to effect substitution of DNA throughout an entire replication period. As illustrated by studies of mouse bone-marrow and spleen cells in the presence or absence of cyclophosphamide, this depot method of BrdU administration greatly simplifies in vivo analysis of sister-chromatid-exchange formation. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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