[An analysis of human marker chromosomes originating from chromosome 21 by using in situ hybridization].

Autor: Zerova TE, Baronova EV, Gorovenko NG, Koblianskaia GN, Buzhievskaia TI, Vorsanova SG, Iurov IuB
Jazyk: ruština
Zdroj: TSitologiia i genetika [Tsitol Genet] 1995 Sep-Oct; Vol. 29 (5), pp. 41-8.
Abstrakt: Four cases of patients with additional marker chromosomes are described. The clinical, cytogenetic and molecular cytogenetic methods have been used for investigation. The identification of marker chromosomes was made by using in situ hybridization and the collection of chromosome-specific DNA probes. All marker chromosomes were determined as originated from chromosome 21 with break-points in the region between 21q11 and 21q22.
Databáze: MEDLINE