| Autor: |
Pogorelyĭ VE, Gaevyĭ MD, Migruev RR, Ivashev MN |
| Jazyk: |
ruština |
| Zdroj: |
Eksperimental'naia i klinicheskaia farmakologiia [Eksp Klin Farmakol] 1995 Sep-Oct; Vol. 58 (5), pp. 19-21. |
| Abstrakt: |
In acute experiments on anesthetized cats with cerebral ischemia in conditions of autohemoperfusion of cerebral and peripheral vessels with a stable volume of blood we found that lithium oxybutirate and new GABA derivatives: LOS 1-84 and LOS 5-79 affect the cerebral blood flow and metabolism in the brain. Prophylactic intravenous injection of lithium oxybutirate did not affect the development of postischemic hyperperfusion but inhibited postischemic hyperperfusion. The compounds prevent the development of postischemic phenomena and promote the recovery of metabolism in the brain. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
|
