| Autor: |
Shen L; China Doping Control Center, National Research Institute of Sports Medicine, Beijing., Xu YX, Zhang CJ, Wu Y, Wang S, Cui KR |
| Jazyk: |
čínština |
| Zdroj: |
Yao xue xue bao = Acta pharmaceutica Sinica [Yao Xue Xue Bao] 1995; Vol. 30 (9), pp. 702-5. |
| Abstrakt: |
A method for the detection and identification of penbutolol and its metabolites in human body fluid by using gas chromatography-mass spectrometry was established. The urine was extracted with diethyl ether-isopropanol and the plasma was extracted with Sep-Pak column. After TMS derivatization the sample was analyzed with GC-MSD. Six metabolites of penbutolol were found in urine sample. The recovery was 90.83% for urine and 85.88% for plasma. The detection limit of penbutolol was 5 pg. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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