[The phenotypic characteristics of healthy carriers of the antigenic structures of the influenza A virus].

Autor: Tsybalova LM, Sominina AA, Popova TL, Filippova IE, Zibina EA, Bekhtereva TA, Konovalova II, Voĭtsekhovskaia EM, Semilutskaia IB
Jazyk: ruština
Zdroj: Zhurnal mikrobiologii, epidemiologii i immunobiologii [Zh Mikrobiol Epidemiol Immunobiol] 1996 Mar-Apr (2), pp. 32-6.
Abstrakt: Highly sensitive methods for the detection of viral antigens with the use of monoclonal or polyclonal enzyme immunoassay test systems, as well as virus-specific nucleic sequences (NS-gene) in polymerase chain reaction, made it possible to establish the fact of long-term asymptomatic virus carriership (AVC) in some of adolescent schoolchildren in a closed group. The occurrence of AVC varied at different phases of the epidemic process. The tendency to AVC was observed in individuals having blood group B (III) and HLA-A9 antigen of the major histocompatibility complex. The development of AVC occurred in the presence of a decreased level of humoral immunity. AVC was mainly registered among individuals, relatively resistant to relapsing clinically pronounced forms of respiratory virus infections.
Databáze: MEDLINE