Autor: |
Brill GM; Abbott Laboratories, Abbott Park, Il. 60064, USA., Kati WM, Montgomery D, Karwowski JP, Humphrey PE, Jackson M, Clement JJ, Kadam S, Chen RH, McAlpine JB |
Jazyk: |
angličtina |
Zdroj: |
The Journal of antibiotics [J Antibiot (Tokyo)] 1996 Jun; Vol. 49 (6), pp. 541-6. |
DOI: |
10.7164/antibiotics.49.541 |
Abstrakt: |
Two novel triterpene sulfates have been isolated from Fusarium compactum by bioactivity-directed fractionation using an assay which measures the inhibition of proteolytic activity of rhinovirus 3C protease on a fluorogenic peptide substrate. The compounds were purified by countercurrent and reverse phase chromatographies. NMR, MS, UV and IR studies revealed two triterpene sulfates, uncommon metabolites of terrestrial fungi. |
Databáze: |
MEDLINE |
Externí odkaz: |
|