Randomized, double blind comparison of brand and generic antibiotic suspensions: II. A study of taste and compliance in children.
| Autor: | El-Chaar GM; St. John's University College of Pharmacy, Jamaica, NY, USA., Mardy G, Wehlou K, Rubin LG |
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| Jazyk: | angličtina |
| Zdroj: | The Pediatric infectious disease journal [Pediatr Infect Dis J] 1996 Jan; Vol. 15 (1), pp. 18-22. |
| DOI: | 10.1097/00006454-199601000-00004 |
| Abstrakt: | Background: The taste of oral liquid medications influences compliance in children. Generic preparations are prescribed to reduce cost and may taste worse than brand name products. Methods: This was a prospective, randomized, double blind, crossover trial of the differences in taste and compliance between brand and generic antibiotic suspensions in children 3 to 14 years of age. Verbal and visual assessment methods were used to assess taste, and compliance was measured by the amount of drug returned after use. Results: Ten children in each of the cephalexin and erythromycin-sulfisoxazole groups did not report that the brand and generic formulations tasted differently. Fifteen children thought that brand trimethoprim-sulfamethoxazole tasted better than the generic preparation. Conclusions: Brand name oral liquid antibiotics do not necessarily taste better than their generic counterparts. Despite preference for the taste of brand trimethoprim-sulfamethoxazole, all of the children in this study were compliant with both brand and generic medications. |
| Databáze: | MEDLINE |
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