Autor: |
Skellern GG, Knight BI, Luman FM, Stenlake JB, McLarty DG, Hooper MJ |
Jazyk: |
angličtina |
Zdroj: |
Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 1977 Apr; Vol. 7 (4), pp. 247-53. |
DOI: |
10.3109/00498257709035782 |
Abstrakt: |
1. Classical and high-pressure liquid chromatographic separations were devised for the separation and isolation of the metabolite 3-methyl-2-thiohydantoin from the urine of patients receiving carbimazole orally. 2. 3-methyl-2-thiohydantoin was identified by comparing its absorption and mass spectral properties with authentic material. 3. 3-methyl-2-thiohydantoin was also detected in the plasma of patients receiving methimazole intravenously. |
Databáze: |
MEDLINE |
Externí odkaz: |
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