Increased uptake of indium-111 pentetreotide up to 10 years after external thoracic irradiation: report of two cases.

Autor: Stoffel M; Department of Nuclear Medicine, University of Louvain (UCL), Mont-Godinne, Belgium., Jamar F, Donckier J, Hainaut P, Decoster P, Beckers C, Pauwels S
Jazyk: angličtina
Zdroj: European journal of nuclear medicine [Eur J Nucl Med] 1996 Jun; Vol. 23 (6), pp. 723-6.
DOI: 10.1007/BF00834537
Abstrakt: Indium-111 pentetreotide scintigraphy was performed in two patients for the localization of recurrent medullary thyroid carcinoma treated by surgery and external radiotherapy 1 and 10 years earlier. A marked uptake of the radiopharmaceutical was demonstrated in the lung areas that had been irradiated. These cases strongly suggest that this uptake is related to pulmonary fibrosis, a well-known complication of radiotherapy, even long after the irradiation. Therefore, attention must be paid to the avoidance of false-positive interpretation of somatostatin receptor scintigraphy in patients previously treated by radiotherapy.
Databáze: MEDLINE