| Autor: |
Leont'ev VK, Kankanian AP |
| Jazyk: |
ruština |
| Zdroj: |
Stomatologiia [Stomatologiia (Mosk)] 1996; Vol. 75 (1), pp. 26-9. |
| Abstrakt: |
Concentration of markers for platelet and leukocyte local activation including platelets factor four, beta-thromboglobulin, granulyte elastate and beta-glucunidase was measured in gingival fluid from patients with gingivitis and periodontitis. It has been shown that there is a statistically significant increase in level of markers in these patients. The increase correlated with degree of periodontal injury. Radioimmune assay of concentrations of platelet-activating factor (PAF) in gingival fluid and gingival tissue was performed. Its concentration also increased in gingivitis and periodontitis depending on intensity of the tissue injury. A close correlation between the PAF concentration has been revealed. It is likely that hypergeneration of PAF in the endothelium is a mechanism for the blood cell activation and accumulation in gingival tissue resulting in its failure due to secretion of different deleterious agents from the activated cells. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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