[Alpha-fetoprotein suppresses keratinocyte proliferation in vitro].

Autor: Voroteliak EA, Vasil'ev AV, Gusev SA, Povaliĭ TM, Terskikh VV
Jazyk: ruština
Zdroj: Izvestiia Akademii nauk. Seriia biologicheskaia [Izv Akad Nauk Ser Biol] 1996 Jan-Feb (1), pp. 117-20.
Abstrakt: The influence of alpha-fetoprotein (AFP) on the proliferation of human epidermal keratinocytes in vitro has been studied. AFP (1p microgram/ ml) inhibits the proliferation of keratinocytes cultivated in a serum-free medium. The addition of fetal bovine serum significantly enhances the effect of AFP in this culture. A similar effect of AFP is observed in a medium with a low content of calcium ions.
Databáze: MEDLINE