| Autor: |
Edmonds HL Jr; Department of Anesthesiology, University of Louisville, KY 40292, USA., Rodriguez RA, Audenaert SM, Austin EH 3rd, Pollock SB Jr, Ganzel BL |
| Jazyk: |
angličtina |
| Zdroj: |
Journal of cardiothoracic and vascular anesthesia [J Cardiothorac Vasc Anesth] 1996 Jan; Vol. 10 (1), pp. 15-23. |
| DOI: |
10.1016/s1053-0770(96)80174-1 |
| Abstrakt: |
This review describes the techniques currently used for quantitative neurophysiologic measurement during cardiac surgery and their potential impact on clinical outcome. Electroencephalography (EEG) characterizes cerebrocortical neuronal electrical activity and was part of some of the earliest cardiopulmonary bypass procedures, yet today it is not widespread use. Each of the common misunderstandings regarding a supposed limitation of this technology is explained. Its major genuine shortcoming, a lack of selectivity, may now be overcome with the combined use of additional monitoring modalities. The influence of intracranial hemodynamics on observed EEG changes may be determined continuously and noninvasively with transcranial Doppler (TCD) ultrasound. TCD provides an indication of sudden change in either blood flow or vascular resistance as well as the detection of emboli. In addition, the metabolic status of cortical neurons can be monitored by regional cerebral venous oxygen saturation (rCVOS) using noninvasive transcranial near-infrared spectroscopy. The % rCVOS tends to remain remarkably stable over a wide range of temperatures, perfusion pressures, and anesthetic states. Marked change in either direction signifies a serious imbalance between oxygen delivery and consumption. Measurement of rCVOS does not require blood flow, pulsatile or otherwise, so that it offers the only means of monitoring during circulatory arrest. By characterizing the dynamic interplay among cerebral hemodynamics, metabolism, and electrogenesis, these technologies permit the rapid detection and correction of potentially hazardous conditions. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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Full Text from ScienceDirect