| Autor: |
Watson BM; Division of Allergy, Immunology and Infectious Diseases, Children's Hospital of Philadelphia, PA 19104, USA., Laufer DS, Kuter BJ, Staehle B, White CJ, Starr SE |
| Jazyk: |
angličtina |
| Zdroj: |
The Journal of infectious diseases [J Infect Dis] 1996 Mar; Vol. 173 (3), pp. 731-4. |
| DOI: |
10.1093/infdis/173.3.731 |
| Abstrakt: |
An investigational tetravalent combined measles, mumps, rubella, and varicella vaccine and measles-mumps-rubella and varicella vaccines at separate injection sites given at the same visit were evaluated with respect to safety and cell-mediated and humoral immune responses at 6 weeks and 1 year after vaccination. Varicella seroconversion rates and lymphocyte proliferation responses were 100% for both vaccine groups at 6 weeks and 1 year. However, the antibody titer to varicella was lower in the combined vaccine group at 6 weeks, but there was no statistical difference in cell-mediated immune responses. One-year geometric mean titers were not statistically different. Seroconversion rates for measles, mumps, and rubella were 100% for both vaccine at 6 weeks and 1 year. Long-term follow-up of these immune responses is planned. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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