A preliminary study of reconstruction of the monkey temporomandibular joint with autogenous tissues.

Autor: Marciani RD; Department of Veterans Affairs, Lexington, KY, USA., Gonty AA, White DK, Traurig HH
Jazyk: angličtina
Zdroj: Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons [J Oral Maxillofac Surg] 1996 Feb; Vol. 54 (2), pp. 191-9.
DOI: 10.1016/s0278-2391(96)90446-2
Abstrakt: Purpose: This study investigated the ability of autogenous pericranium-muscle and cranial bone to restore form and function of the temporomandibular joint (TMJ).
Materials and Methods: A right TMJ discectomy, condylectomy, vertical ramus osteotomy with superior repositioning of the proximal fragment, and a cranial bone graft to the mandibular angle were performed in 12 cynomolgus monkeys. Clinical, histologic, and autoradiographic evaluation was done at intervals beginning at 3 days and continuing up to 78 weeks.
Results: No significant postoperative sequela were identified in any of the monkeys. Jaw mobility and function were restored. Gross morphologic condylar changes were observed. The pericranium-muscle grafts did not differentiate into normal disc-like structures and a cartilage cap did not cover the condyle stump head.
Conclusions: The results of this study suggest that the previous TMJ function was restored. However, the histologic changes observed were consistent with advanced degenerative joint disease.
Databáze: MEDLINE