| Autor: |
Macina RA; Wistar Institute, Philadelphia, Pennsylvania 19104, USA., Morii K, Hu XL, Negorev DG, Spais C, Ruthig LA, Riethman HC |
| Jazyk: |
angličtina |
| Zdroj: |
Genome research [Genome Res] 1995 Oct; Vol. 5 (3), pp. 225-32. |
| DOI: |
10.1101/gr.5.3.225 |
| Abstrakt: |
Large terminal fragments of human chromosomes 2p, 6p, 8q, 12q, and 18q were cloned using yeast artificial chromosomes (YACs). RecA-assisted restriction endonuclease (RARE) cleavage analysis of genomic DNA samples from II unrelated individuals using YAC-derived probes confirmed the telomeric localizations of the half-YACs studied. The cloned fragments provide telomeric closure of maps for the respective chromosome arms and will supply the reagents needed for analyzing and sequencing these distal subtelomeric regions. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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