Abstrakt: |
Technicon H-1, an automated flow blood analyzer with determination of the leukocytic formula of cellular peroxidase activity for differentiated estimation, is used at the laboratory of N. N. Blokhin Cancer Research Center, Russian Academy of Medical Sciences. Analysis of the incidence of changes in the basic and additional characteristics recorded by the device in analyses of peripheral blood from 76 hematological patients, mainly with hemoblastosis variants, showed that if the number of blast cells were up to 45%, the analyzer recorded from 3 to 7 additional "alarm" signals, and a "blast+" signal in approximately 52% of these; if the count of blast cells were over 45%, the signal "blast+" was shown by the analyzer in 100% cases. A peroxidase channel helps detect the lymphoid or myeloid trend of leukemic cell differentiation. |