[Clastogenic activity of dietary sugar substitutes].

Autor: Durnev AD, Oreshchenko AV, Kulakova AV, Beresten' NF, Seredenin SB
Jazyk: ruština
Zdroj: Voprosy meditsinskoi khimii [Vopr Med Khim] 1995 Jul-Aug; Vol. 41 (4), pp. 31-3.
Abstrakt: The present paper describes the possible clastogenic activity of the following synthetic sugar substitutes, such as cyclamate in daily doses of 11 and 110 mg/kg, saccharin, 5 and 50 mg/kg, acesulfam, 15 and 150 mg/kg, sucralose, 15 and 150 mg/kg, aspartame, 40 and 400 mg/kg, orally given to C57Bl/6 mice during 5 days. No clastogenic activity was found in the compounds tested.
Databáze: MEDLINE