| Autor: |
Crowley ST; Division of Nephrology, National Naval Medical Center, Bethesda, Maryland, USA., Morrissey RL, Silverman ED, Yudt WM, Hirszel P |
| Jazyk: |
angličtina |
| Zdroj: |
Renal failure [Ren Fail] 1995 Sep; Vol. 17 (5), pp. 589-93. |
| DOI: |
10.3109/08860229509037623 |
| Abstrakt: |
To evaluate the possibility that the placement of arteriovenous anastomosis (a/v a) may lead to the attenuation of glomerular hyperfiltration, we studied 5 nondiabetic patients before and after creation of vascular access for hemodialysis. Patients received no EPO and antihypertensive therapy was discontinued 24 h before each study. Cardiac output (CO) and a/v a flow rates were measured by Doppler echo, and GFR and ERPF by plasma decay curves of Tc99m DTPA and 131I-hippuran, respectively. Other parameters were calculated by standard formulas. Augmentation of CO and decrease in systemic vascular resistance occurred in all patients (p = 0.05), yet renal findings were less predictable since only three patients showed a decrease in renal vascular resistance and filtration fraction post a/v a. Thus, there is a discordant pattern of renal hemodynamic response to the creation of a/v a in end-stage renal disease and further studies are needed to better define the subset of patients who are prone to renal vasodilation after the placement of a/v a. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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