Autor: |
Golconda MS; Division of Nephrology and Internal Medicine, Mayo Clinic Rochester, MN 55905, USA., Larson TS, Kolb LG, Kumar R |
Jazyk: |
angličtina |
Zdroj: |
Mayo Clinic proceedings [Mayo Clin Proc] 1996 Jan; Vol. 71 (1), pp. 32-6. |
DOI: |
10.4065/71.1.32 |
Abstrakt: |
Hypercalcemia occurs in 10 to 30% of renal transplant recipients and is most often due to persistent hyperparathyroidism. Herein we describe a patient with a history of hyperparathyroidism who sought medical assessment because of recurrence of hypercalcemia 7 years after a successful renal transplantation. The hypercalcemia was associated with a normal serum phosphate level, a low to normal parathyroid hormone level, virtually undetectable levels of parathyroid hormone-related protein, and increased 1,25-dihydroxyvitamin D levels. Further assessment led to the diagnosis of an underlying lymphoma. To our knowledge, this is the first report of 1,25-dihydroxyvitamin D-mediated hypercalcemia in a renal transplant recipient with lymphoma. The possibility of an underlying lymphoproliferative disorder should be considered in the differential diagnosis of hypercalcemia in a renal transplant recipient. |
Databáze: |
MEDLINE |
Externí odkaz: |
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