[The modification of Bacillus intermedius ribonuclease by urea derivatives].

Autor: Kurinenko BM, Kalacheva NV, Fedotova NR, Bulgakova RSh
Jazyk: ruština
Zdroj: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] [Antibiot Khimioter] 1995 May; Vol. 40 (5), pp. 16-9.
Abstrakt: The results of the "Bacillus intermedius" RNAase modification by urea derivatives are presented. The modifiers synthesized for that purpose were the following: N-(4-chlorbenzoyl)-N'-benzolsulfonyl urea (M1) and N-(4-chlorbenzoyl)carbomoyl-epsilon-aminocapronic acid (M2). It was shown that RNAase modified by M2 stimulated the cell general metabolism by the test of the cell absorption of neutral red and had a more marked ability to disrupt RNA of the cell plasmatic membranes in comparison to that of the native enzyme.
Databáze: MEDLINE