Autor: |
Kamat AK; Department of Biochemistry and Molecular Biology, Lederle Graduate Research Center, University of Massachusetts, Amherst., Rocchi M, Smith DI, Miller OJ |
Jazyk: |
angličtina |
Zdroj: |
Somatic cell and molecular genetics [Somat Cell Mol Genet] 1993 Mar; Vol. 19 (2), pp. 203-8. |
DOI: |
10.1007/BF01233534 |
Abstrakt: |
Lamins A and C are products of alternate splicing of one transcript from a single gene. We have isolated a partial cDNA, cE1-2, whose 800-bp sequence is 99% identical to the 3' untranslated region of the lamin A/C gene. We report here the mapping of this gene and a closely related sequence to human chromosomes 1 and 10, more specifically, to 1q12.1-q23. The localization of cE1-2 hybridizing sequences to two different chromosomes suggests that one of these loci represents an as yet unknown member of the lamin gene family, either a pseudogene or an expressed gene. |
Databáze: |
MEDLINE |
Externí odkaz: |
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