Autor: |
Janszen BP; Department of Herd Health and Reproduction, University of Utrecht, The Netherlands., Bevers MM, Ravenshorst MM, van der Weijden GC, Dieleman SJ, Taverne MA |
Jazyk: |
angličtina |
Zdroj: |
Journal of reproduction and fertility [J Reprod Fertil] 1993 Mar; Vol. 97 (2), pp. 457-61. |
DOI: |
10.1530/jrf.0.0970457 |
Abstrakt: |
The influence of luteolysis on myometrial activity in late pregnant cows was studied by measuring electromyographic (EMG) activity and concentrations of progesterone and 13,14-dihydro-15-keto-prostaglandin F2 alpha (PGFM) in maternal arterial plasma of five cows. Application of two ear implants containing progestagen at day 261 of gestation was followed by an injection of a luteolytic dose of a prostaglandin F2 alpha (PGF2 alpha) analogue (PG) on day 264. Calving was initiated by removal of the implants and a single injection of 5 mg flumethasone on day 270. All calves were born alive at a mean interval of 36 h. After 4 h of hyperactivity immediately following the injection of PG, myometrial activity was almost completely absent for 20 h; before luteolysis the total duration of EMG activity was 7.21 +/- 0.31 min h-1 (mean +/- SEM), during the 4 h after PG 23.61 +/- 3.40 min h-1, and during inhibition 2.70 +/- 0.87 min h-1. After the last period, EMG activity recurred and reached values of 14.52 +/- 3.07 and 11.17 +/- 2.87 min h-1, on days 265 and 269, respectively. Concentrations of progesterone in maternal plasma decreased from 4.17 to 1.14 ng ml-1 within 12 h after PG, whereas concentrations of PGFM in plasma remained low, varying from 15 to 30 pg ml-1. After removal of the implants and injection of flumethasone on day 270, EMG activity increased without an inhibitory phase and reached maximum values around the time of expulsion of the calves.(ABSTRACT TRUNCATED AT 250 WORDS) |
Databáze: |
MEDLINE |
Externí odkaz: |
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