Comorbidity in psychosis at first hospitalization.
| Autor: | Strakowski SM; Epidemiology Laboratory, McLean Hospital, Belmont, Mass., Tohen M, Stoll AL, Faedda GL, Mayer PV, Kolbrener ML, Goodwin DC |
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| Jazyk: | angličtina |
| Zdroj: | The American journal of psychiatry [Am J Psychiatry] 1993 May; Vol. 150 (5), pp. 752-7. |
| DOI: | 10.1176/ajp.150.5.752 |
| Abstrakt: | Objective: The authors sought to determine the prevalence and effects of medical and psychiatric comorbidity on initial outcome in a group of patients experiencing a first episode of psychosis. Method: Patients with a first episode of psychosis who were consecutively admitted to a hospital (N = 102) were examined for the presence of psychiatric and medical disorders. Patients were given psychiatric diagnoses with the use of the Structured Clinical Interview for DSM-III-R and were rated weekly on symptom rating scales. Outcome variables at discharge were final symptom rating scale scores, length of hospitalization, and recovery on the basis of operationalized criteria. Results: Comorbid diagnoses were present in 52.0% (N = 53) of the patients, and 37.7% (N = 20) had multiple comorbid diagnoses. The most common comorbid diagnosis was substance abuse. Patients with affected psychoses were significantly more likely than those with nonaffective psychoses to have a comorbid substance abuse diagnosis. Patients with psychiatric comorbidity had poorer initial outcomes, while those with medical comorbidity had fewer symptoms at discharge. Conclusions: Comorbidity is common and may be a useful predictor of the outcome of a first episode of psychosis. |
| Databáze: | MEDLINE |
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