| Autor: |
Van den Berge D; Oncologic Centre AZ-VUB, Department of Radiotherapy, Eenheid Kanker, Vrije Universiteit Brussel, Belgium., Bruyneel E, Distelmans W, Van Belle S, Krikonian A, Breillout F, Storme G |
| Jazyk: |
angličtina |
| Zdroj: |
Anticancer research [Anticancer Res] 1993 Jan-Feb; Vol. 13 (1), pp. 273-7. |
| Abstrakt: |
5'-nor-anhydrovinblastine (Navelbine) is a hemisynthetic Vinca alkaloid for which a selectivity for mitotic microtubules has been demonstrated. In previous studies, we have demonstrated an anti-invasive effect of other Vinca alkaloids. Here the results of in vitro and in vivo assays concerning the effect of 5'-nor-anhydrovinblastine on growth and invasion of MO4 cells are presented. It is demonstrated that at cytostatic concentrations, 5'-nor-anhydrovinblastine also has an anti-invasive effect. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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