Estrogen receptor variant and hypertension in women.

Autor: Lehrer S; Department of Radiation Therapy, Mount Sinai Medical Center, New York, NY 10029., Rabin J, Kalir T, Schachter BS
Jazyk: angličtina
Zdroj: Hypertension (Dallas, Tex. : 1979) [Hypertension] 1993 Apr; Vol. 21 (4), pp. 439-41.
DOI: 10.1161/01.hyp.21.4.439
Abstrakt: Eighty-eight women visiting a gynecologist were tested for an estrogen receptor B-variant allele. The women were ethnically and racially homogeneous to a large degree. They were from a suburb of Long Island, and most were white. The 12% incidence of hypertension in women with the estrogen receptor wild-type allele is comparable to the 13-32% incidence in the general population of women aged 55-64 years. However, the 48% incidence of hypertension in women with the estrogen receptor B-variant allele is considerably higher than in the general population of women in this age group. We conclude that the presence of the estrogen receptor B-variant allele might have increased the prevalence of hypertension in the women in this study.
Databáze: MEDLINE