Prolonged use of isoflurane in a patient with tetanus.

Autor: Stevens JJ; Ipswich Hospital., Griffin RM, Stow PJ
Jazyk: angličtina
Zdroj: British journal of anaesthesia [Br J Anaesth] 1993 Jan; Vol. 70 (1), pp. 107-9.
DOI: 10.1093/bja/70.1.107
Abstrakt: We describe a patient with tetanus, who received isoflurane for sedation to facilitate controlled mechanical ventilation. Isoflurane was administered for 34 days, resulting in a sustained serum inorganic fluoride ion concentration in excess of 50 mumol litre-1 and a peak serum inorganic fluoride ion concentration of 87 mumol litre-1. Although these concentrations are potentially nephrotoxic, no toxicity was evident clinically.
Databáze: MEDLINE