| Autor: |
Murtaugh RJ; Department of Medicine, School of Veterinary Medicine, Tufts University, North Grafton, MA 01536., Matz ME, Labato MA, Boudrieau RJ |
| Jazyk: |
angličtina |
| Zdroj: |
Journal of the American Veterinary Medical Association [J Am Vet Med Assoc] 1993 Jan 15; Vol. 202 (2), pp. 251-6. |
| Abstrakt: |
A randomized, double-blind, controlled study was performed with 18 arthritic dogs administered aspirin (25 mg/kg of body weight, PO, q 8 h) and excipient (control group) or aspirin and misoprostol (100 micrograms, PO, q 8 h). Dogs in the misoprostol (n = 10) and control (n = 8) groups were primarily compared by use of sequential gastroduodenoscopy, changes in PCV, and prevalence of clinical signs of gastrointestinal disturbance over a 14-day treatment period. The misoprostol/aspirin-treated group had significantly (P < 0.05) less gastroduodenal hemorrhage and ulceration and a significantly (P < 0.05) lower prevalence of vomiting than did the control group. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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