| Autor: |
Prince MR; Department of Radiology, Massachusetts General Hospital, Boston 02114., Frisoli JK |
| Jazyk: |
angličtina |
| Zdroj: |
The American journal of clinical nutrition [Am J Clin Nutr] 1993 Feb; Vol. 57 (2), pp. 175-81. |
| DOI: |
10.1093/ajcn/57.2.175 |
| Abstrakt: |
The accumulation of beta-carotene in serum and skin was evaluated in human volunteers. A single 51-mg dose of beta-carotene given in the absence of dietary fat resulted in no detectable change in serum beta-carotene. The same dose administered with 200 g fat increased serum beta-carotene 2.5-fold at 40 h. Similarly, administering beta-carotene daily in three divided doses with meals raised the serum beta-carotene concentration three times as high compared with the same total dose administered once a day; both regimens had the same time constant for serum accumulation; 9-10 d. Remittance measurements of skin color demonstrated that the accumulation of beta-carotene in skin was delayed by up to 2 wk compared with serum accumulation. These data indicate that beta-carotene absorption requires dietary fat and is enhanced by administering with meals but there is a long time constant for serum (10 d) and tissue (several weeks) accumulation. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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