Phenytoin and dyskinesias: a report of two cases and review of the literature.

Autor: Harrison MB; Department of Neurology, University of Virginia Health Sciences Center Charlottesville 22908., Lyons GR, Landow ER
Jazyk: angličtina
Zdroj: Movement disorders : official journal of the Movement Disorder Society [Mov Disord] 1993; Vol. 8 (1), pp. 19-27.
DOI: 10.1002/mds.870080104
Abstrakt: Dyskinesia is a recognized but uncommon side-effect of treatment with phenytoin. Two additional cases of dyskinesia during treatment with phenytoin are described; both had radiographically documented thalamic infarctions. The reported experience to date with movement disorders induced by phenytoin is reviewed and the clinical features summarized. The available experimental evidence addressing the mechanism underlying this side effect is discussed.
Databáze: MEDLINE