| Autor: |
Miller-Blair DJ; Kaiser-Permanente Medical Center, South Sacramento, CA., Robbins DL |
| Jazyk: |
angličtina |
| Zdroj: |
Geriatrics [Geriatrics] 1993 Jun; Vol. 48 (6), pp. 28-31, 35-8. |
| Abstrakt: |
Rheumatoid arthritis (RA) is a chronic systemic inflammatory disease that occurs two to four times as often in women as in men and increases in incidence with advancing age. It affects synovial-lined joints and can also affect the pulmonary, cardiac, nervous, integumentary, and reticuloendothelial systems. RA is manifested clinically by malaise and fatigue, followed by a symmetric pattern of joint inflammation characterized by pain and stiffness. RA most likely occurs in the setting of a genetically predisposed individual, triggered by infectious agents or endogenous antigens. Many of the newer treatments being studied involve blocking cytokine-mediated interactions between cells of the synovium. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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