Comparative studies of intracellular activity, secretion and multiple forms spectra of human skin fibroblast alpha-L-fucosidase in the normaland after sucrose load.

Autor: Beyer EM; Institute of Biomedical Chemistry, Russian Academy of Medical Sciences, Moscow., Ivleva TS, Artykova GT, Wiederschain GYa
Jazyk: angličtina
Zdroj: Biochemistry and molecular biology international [Biochem Mol Biol Int] 1993 Jun; Vol. 30 (2), pp. 367-75.
Abstrakt: Activity and multiple forms of intracellular and secreted alpha-L-fucosidases from human skin fibroblasts were studied in normal and sucrose-loaded cells--modelling intralysosomal nonhydrolyzable products' accumulation in vitro. Certain differences in secretion levels were found after sucrose load for alpha-L-fucosidases from embryonal and postnatal cell lines. Different effects of sucrose load on multiple forms' spectra of the intracellular and secreted alpha-L-fucosidases from embryonal and postnatal fibroblasts were revealed.
Databáze: MEDLINE