[The effect of pyrazole on the conformational state of cell membrane phospholipids].
| Autor: | Nasibullin RS, Sultanova VS, Zagitov GN, Zeleev MKh |
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| Jazyk: | ruština |
| Zdroj: | Biofizika [Biofizika] 1993 Jul-Aug; Vol. 38 (4), pp. 684-6. |
| Abstrakt: | A change of conformation of phospholipids in the presence of pyrazole was studied by the method of 1H-NMR spectroscopy with the use of hydrophilic paramagnetic probes Pr3+. It was shown that the ratio of transformation of the polar groups of the bilayer surface of sonicated phosphatidyl-choline increased in the presence of pyrazole as compared to the experimental values of the induced pseudocontact shifts of the phosphorylcholine groups. It was established that the earlier discovered complexes of pyrazole-phospholipids in the inert solution exhibited in the water phase. |
| Databáze: | MEDLINE |
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