Effects of age on lactose malabsorption in Oklahoma Native Americans as determined by breath H2 analysis.

Autor: Caskey DA, Payne-Bose D, Welsh JD, Gearhart HL, Nance MK, Morrison RD
Jazyk: angličtina
Zdroj: The American journal of digestive diseases [Am J Dig Dis] 1977 Feb; Vol. 22 (2), pp. 113-6.
DOI: 10.1007/BF01072952
Abstrakt: Breath H2 excretion was used to determine lactose malabsorption in 30 health females and 30 healthy males between the ages of 3 and 64 yr who were at least 7/8 Native American. The test meal consisted of 5 ml reconstituted nonfat dry milk (0.25 g lactose) per kg of body weight. On the basis of breath H2 tests in 15 control subjects with normal oral lactose tolerance tests, a response factor of 20 ppm was selected as the upper limit for lactose absorbers. Of the 60 subjects in the study group, 36 (60%) were classified as lactose malabsorbers since they had a response factor of 20 ppm or greater of breath H2. Only 3 of 20 children (15%) who were under the age of 12 yr were nondigesters of the small lactose dose used in this study. Approximately 82 percent (82.5%) of subjects who were 13 yr and older were lactose malabsorbers. Adolescence appears to be the period in which malabsorption of lactose becomes evident in Native North Americans.
Databáze: MEDLINE