| Autor: |
Koehorst SG; Department of Endocrinology, Academic Hospital Utrecht, The Netherlands., Jacobs HM, Thijssen JH, Blankenstein MA |
| Jazyk: |
angličtina |
| Zdroj: |
British journal of cancer [Br J Cancer] 1993 Aug; Vol. 68 (2), pp. 290-4. |
| DOI: |
10.1038/bjc.1993.330 |
| Abstrakt: |
When a ligand binding or enzyme immunoassay is used, meningiomas are found to be rich in progestin receptors (PR) whereas oestrogen receptors (ER) are virtually undetectable. A protein that can bind to an oestrogen responsive element (ERE) was detected in meningiomas, by using the band-shift assay. The binding of ER to the ERE is inhibited by the anti-ER monoclonal antibody ER-P31, which is directed to the A/B domain of the ER, indicating that the binding protein is an ER-like protein. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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