| Autor: |
Sherwin RP, Kaufman C, Dermer GR, Monroe SA |
| Jazyk: |
angličtina |
| Zdroj: |
Cancer [Cancer] 1977 Jan; Vol. 39 (1), pp. 178-85. |
| DOI: |
10.1002/1097-0142(197701)39:1<178::aid-cncr2820390129>3.0.co;2-a |
| Abstrakt: |
A tumor excised from the thyroid gland has been shown by electron microscopy to contain distinctive, intranuclear rodlets. This is the first report of such rodlets in a non-neuronal human tumor. While the parathyroid-like hormonal activity, histopathology, and clinical course are consistent with a parathyroid adenoma, the finding of the rodlets raises the question of origin from a special, neuron-related cell of the parathyroid or thyroid. The unusual cellular granularity and the abundant interstitial fibrillae also suggest an unusual cell of origin. Alternatively, a special metabolic activity may account for the rodlets, or they may have been overlooked in prior studies of adenomas. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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