Determination of the percentage purity, active ingredients and other parameters in paracetamol and chloroquine syrups.

Autor: Udosen EO; Department of Biochemistry, College of Medical Sciences, University of Calabar, Nigeria.
Jazyk: angličtina
Zdroj: The Central African journal of medicine [Cent Afr J Med] 1993 Jan; Vol. 39 (1), pp. 8-10.
Abstrakt: In this paper the percentage purity, active ingredients, specific gravity and the pH of paracetamol and chloroquine syrups were determined. For paracetamol the percentage purity ranged from 102.6-106.67, while the active ingredients (in mg/5 ml base) ranged from 123.2-128. The specific gravity ranged from 1.13-1.24 and the pH from 4.16-5.32. For the chloroquine the percentage purity ranged from 97-106.3, and the active ingredient 48.5-53.13, the specific gravity 1.17-1.27 and the pH 2.44-4.17. The results are discussed in relation to the purity, active ingredients and sources of the drugs. The drugs were coded. The paracetamol had a code of 1p-5p while the chloroquine was coded from 1c-5c.
Databáze: MEDLINE