Neonatal hemochromatosis associated with maternal autoantibodies against Ro/SS-A and La/SS-B ribonucleoproteins.

Autor: Schoenlebe J; Institut fuer Pathologie Georg Schmorl, Staedtisches Klinikum, Dresden, Germany., Buyon JP, Zitelli BJ, Friedman D, Greco MA, Knisely AS
Jazyk: angličtina
Zdroj: American journal of diseases of children (1960) [Am J Dis Child] 1993 Oct; Vol. 147 (10), pp. 1072-5.
DOI: 10.1001/archpedi.1993.02160340058014
Abstrakt: Liver disease in the fetus and neonate may be associated with maternal Sjögren's syndrome (neonatal lupus erythematosus). The infant of a mother with Sjögren's syndrome and high anti-Ro/SS-A and anti-La/SS-B antibody titers presented at 2 1/2 weeks of age with overwhelming hepatic insufficiency and died at 6 weeks of age. Autopsy confirmed the antemortem diagnosis of neonatal hemochromatosis. We discuss the possibility of a relationship between these two conditions.
Databáze: MEDLINE